Narutaki Laboratory

Department of Soft Matter and Biomedical Engineering, Institute of Biomaterials and Bioengineering,
Tokyo Medical and Dental University
Department of Energy Engineering, Graduate School of Engineering, Nagoya University



  • Tatsuki Oishi, Ayae Sugawara-Narutaki, Rintaro Takahashi
    Supracolloidal step-growth polymerization of isotropic silica nanoparticles: a time-resolved small-angle X-ray scattering study
    Polym. J. in press.
  • Shota Yamada, Kaori Yamada, Ayae Sugawara-Narutaki, Yoshinobu Baba, Hiroshi Yukawa
    Near-infrared-II fluorescence/magnetic resonance double modal imaging of transplanted stem cells using lanthanide co-doped gadolinium oxide nanoparticles
    Analytical Sciences, in press.
  • Ayae Sugawara-Narutaki, Jin Nakamura, Chikara Ohtsuki
    Elastin-like hydrogels as tissue regeneration scaffolds
    Hydrogels for Tissue Engineering and Regenerative Medicine (Eds J. M. Oliveira, J. Silva-Correia, R. L. Reis), pp.65-77 (2024)


  • Kota Aoki, Ayae Sugawara-Narutaki, Rintaro Takahashi
    Polymeric Sol–Gel Transition with the Diverging Correlation Length Verified by Small-Angle X-ray Scattering
    The Journal of Physical Chemistry Letters, 14(46), 10396-10401 (2023).
  • Kazushi Ogata, Mineo Hashizume, Rintaro Takahashi, Tasuku Hamaguchi, Hiroshi Jinnai, Shin-ichi Yusa
    Formation of Polyion Complex Aggregate Formed from a Cationic Block Copolymer and Anionic Polysaccharide
    Langmuir, 39(46), 16484-17493 (2023).
  • Rintaro Takahashi, Kazuki Yamamoto, Ryo Sugahara, Ryusuke Otake, Keisuke Hayashi, Jin Nakamura, Chikara Ohtsuki, Sadahito Aoshima, Ayae Sugawara-Narutaki
    In situ and ex situ studies of ring-like assembly of silica nanoparticles in the presence of poly (propylene oxide)–poly (ethylene oxide) block copolymers
    Langmuir, 39(32), 11379-11387 (2023).
  • Kengo Takagi, Shukanta Bhowmik, Kang-Ting Huang, Chun-Jen Huang, Rintaro Takahashi, Shin-ichi Yusa
    Complex formation of pendant lysine residue-containing zwitterionic random copolymer with copper (II)
    Polym. J., 55, 1075-1083 (2023).
  • Shukanta Bhowmik, Thu Thao Pham, Rintaro Takahashi, Dongwook Kim, Hideki Matsuoka, Kazuhiko Ishihara, Shin-ichi Yusa
    Preparation of Water-Soluble Polyion Complex (PIC) Micelles with Random Copolymers Containing Pendant Quaternary Ammonium and Sulfonate Groups
    Langmuir, 39(23), 8120-8129 (2023).
  • Riku Yamanaka, Ayae Sugawara-Narutaki, Rintaro Takahashi
    In Situ Monitoring of Polymerization-Induced Self-Assembly and Gelation During the Synthesis of Triblock Copolymers via Time-Resolved Small-Angle X-ray Scattering and Rheology
    Macromolecules, 56(11), 4354-4361 (2023).
  • Shota Yamada, Hiroshi Yukawa, Koudai Kitamura, Toshiki Mizumaki, Yasuma Yoshizumi, Tomomi Oohara, Eri Nanizawa, Fumika Hirano, Kazuhide Sato, Ayae Sugawara-Narutaki, Tetsuya Ishikawa, Yoshinobu Baba
    In vivo real-time quantum dots imaging to track transplanted adipose stem cells in different inflammatory states of acute liver failure mice
    Cell Transplantation, 32, 09636897231176442 (11 pages) (2023).
  • Kazuki Natsume, Jin Nakamura, Kazuhide Sato, Chikara Ohtsuki, Ayae Sugawara-Narutaki
    Biological Properties of Self-Assembled Nanofibers of Elastin-Like Block Polypeptides for Tissue-Engineered Vascular Grafts: Platelet Inhibition, Endothelial Cell Activation and Smooth Muscle Cell Maintenance
    Regenerative Biomaterials, 10, rbac111 (10 pages) (2023).
  • Tatsuya Mizuno, Mikihiro Hayashi, Rintaro Takahashi
    Pseudo bimodal elastomers prepared using macro cross-linkers with multiple divinyl side groups and the unusual tensile properties
    Macromol. Rapid Commun., 44(5), 2200936 (7 pages) (2023).
  • Yoko Mizoue, Rintaro Takahashi, Kazuo Sakurai, Sin-ichi Yusa
    Thermo-responsive Polymer Micelle with Liquid Crystalline Core
    Polymers, 15(3), 770 (14 pages) (2023).


  • Koki Ono, Takashi Koide, Kenji Ishikawa, Hiromasa Tanaka, Hiroki Kondo, Ayae Sugawara-Narutaki, Yong Jin, Shigeo Yasuhara, Masaru Hori, Wakana Takeuchi
    Biocompatibility of Conformal Silicon Carbide on Carbon Nanowall Scaffolds
    Japanese Journal of Applied Physics, 62, SA1017 (2022).
  • Shota Yamada, Hiroshi Yukawa, Kaori Yamada, Yuki Murata, Jun-ichiro Jo, Masaya Yamamoto, Ayae Sugawara-Narutaki, Yasuhiko Tabata, Yoshinobu Baba
    In Vivo Multimodal Imaging of Stem Cells Using Nanohybrid Particles Incorporating Quantum Dots and Magnetic Nanoparticles
    Sensors, 22(15), 5705 (10 pages)(2022)
  • Structure and Rheology of Poly(vinylidene difluoride-co-hexafluoropropylene) in an Ionic Liquid: The Solvent Behaves as a Weak Cross-Linker through Ion–Dipole Interaction
    Macromolecules, 55(13), 5591-5600 (2022).
  • Taishi Yokoi, Akiyoshi Mio, Jin Nakamura, Ayae Sugawara-Narutaki, Masakazu Kawashita, Chikara Ohtsuki
    Transformation Behaviour of Salts Composed of Calcium Ions and Phosphate Esters with Different Linear Alkyl Chain Structures in a Simulated Body Fluid Modified with Alkaline Phosphatase
    Sci. Tech. Adv. Mater., 23(1), 341-351 (2022).
    [Editor's Choice Collection]
  • Thu Thao Pham, Rintaro Takahashi, Tien Duc Pham, Shin-ichi Yusa
    Stable Water-soluble Polyion Complex Micelles Composed of Oppositely Charged Diblock Copolymers and Reinforced by Hydrophobic Interactions
    Chem. Lett., 51(8) 877-880 (2022).
  • Rintaro Takahashi, Theyencheri Narayanan, Shin-ichi Yusa, Takahiro Sato
    Formation Kinetics of Polymer Vesicles from Spherical and Cylindrical Micelles Bearing the Polyelectrolyte Complex Core Studied by Time-Resolved USAXS and SAXS
    Macromolecules, 55(2), 684-695 (2022).


  • Yusuke Sugioka, Jin Nakamura, Chikara Ohtsuki, Ayae Sugawara-Narutaki
    Thixotropic Hydrogels Composed of Self-Assembled Nanofibers of Double-Hydrophobic Elastin-Like Block Polypeptides
    Int. J. Mol. Sci., 22(8), 4104 (12 pages) (2021).
  • Yusuke Sugioka, Jin Nakamura, Chikara Ohtsuki, Ayae Sugawara-Narutaki
    Thixotropic Hydrogels Composed of Self-Assembled Nanofibers of Double-Hydrophobic Elastin-Like Block Polypeptides
    Int. J. Mol. Sci., 22(8), 4104 (12 pages) (2021).
  • Yusuke Sugioka, Jin Nakamura, Chikara Ohtsuki, Ayae Sugawara-Narutaki
    Thixotropic Hydrogels Composed of Self-Assembled Nanofibers of Double-Hydrophobic Elastin-Like Block Polypeptides
    Int. J. Mol. Sci., 22(8), 4104 (12 pages) (2021).
  • Sungho Lee, Tatsuya Miyajima, Ayae Sugawara-Narutaki, Katsuya Kato, Fukue Nagata
    Development of Paclitaxel-Loaded Poly (Lactic Acid)/Hydroxyapatite Core–Shell Nanoparticles as a Stimuli-Responsive Drug Delivery System
    R. Soc. Open Sci., 8(3), 202030 (9 pages) (2021).
  • Jin Nakamura, Ryoya Ito, Ryohei Kozaki, Ayae Sugawara-Narutaki, Chikara Ohtsuki
    Organic Modification of Layered Zirconium Phosphate/Phosphonate for Controlled Release of Therapeutic Inorganic Ions
    Sci. Tech. Adv. Mater., 22(1), 1000-1012 (2021).
  • Jiayun Han, Rintaro Takahashi, Chen Kuang, Takahiro Sato
    Phase Separation Behavior of Aqueous Poly(N-isopropylacrylamide) Solutions Studied by Scattering Experiments
    Langmuir, in press.
  • Seiya Suzuki, Sungh Lee, Tatsuya Miyajima, Katsuya Kato, Ayae Sugawara-Narutaki, Makoto Sakurai, Fukue Nagata
    Evaluation of Drug-Loading Ability of Poly(Lactic Acid)/Hydroxyapatite Core–Shell Particles
    Materials, 14(8), 1959(11 pages) (2021).
  • Jin Nakamura, Yuna Suzuki, Ryosuke Narukawa, Ayae Sugawara-Narutaki, Chikara Ohtsuki
    Preparation of Layered Calcium SilicateOrganically Modified with Two Types of Functional Groups for Varying Chemical Stability
    J. Asian Ceram. Soc., 9(1), 113-123 (2021).
  • Ayae Sugawara-Narutaki, Jin Nakamura, Chikara Ohtsuki
    Polymer-Induced Liquid Precursors (PILPs) and Bone Regeneration
    Bioceramics: From Macro to Nanoscale (Eds by Akiyoshi Osaka and Roger Narayan), pp.391‒398, Elsevier (2021). [Book Chapter]
  • Jin Nakamura, Ayae Sugawara-Narutaki, Chikara Ohtsuki
    Bioactive Ceramics: Past and Future
    Bioceramics: From Macro to Nanoscale (Eds by Akiyoshi Osaka and Roger Narayan), pp.377‒388, Elsevier (2021). [Book Chapter]


  • Jin Nakamura, Kanta Endo, Ayae Sugawara-Narutaki, Chikara Ohtsuki
    Human Stem Cell Response to Layered Zirconium Phosphate
    RSC Adv., 10(59), 36051‒36057 (2020).
  • Fumio Asai, Takahiro Seki, Ayae Sugawara-Narutaki, Kazuhide Sato, Jérémy Odent, Olivier Coulembier, Jean-Marie Raquez, Yukikazu Takeoka
    Tough and 3D-Printable Poly(2-methoxyethyl Acrylate)-Silica Composite Elastomer with Anti-Platelet Adhesion Property
    ACS Appl. Mater. Interfaces, 12(41), 46621‒46628 (2020).
  • Koichiro Hayashi, Atsuto Tokuda, Jin Nakamura, Ayae Sugawara-Narutaki, Chikara Ohtsuki
    Tearable and Fillable Composite Sponges Capable of Heat Generation and Drug Release in Response to Alternating Magnetic Field
    Materials, 13(16), 3637(12 pages) (2020).
  • Ayae Sugawara-Narutaki, Yukiko Kamiya
    Designer Biopolymers: Self-Assembling Proteins and Nucleic Acids
    Int. J. Mol. Sci., 21(9), 3276(3 pages) (2020). [Editorial]
  • Ayae Sugawara-Narutaki
    Bioinspired Synthesis of Silica Nanocups ‒Polymer-Mediated Self-Assembly of Inorganic Nanoparticles
    Impact, 2020(1), 38‒40 (2020). [Commentary]